Increase in the nuclear localization of PTEN by the Toxoplasma GRA16 protein and subsequent induction of p53‐dependent apoptosis and anticancer effect

This study investigated the efficacy of Toxoplasma GRA16, which binds to herpes virus‐associated ubiquitin‐specific protease (HAUSP), in anticancer treatment, and whether the expression of GRA16 in genetically modified hepatocellular carcinoma (HCC) cells (GRA16‐p53‐wild HepG2 and GRA16‐p53‐null Hep...

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Detalles Bibliográficos
Autores principales: Kim, Sang‐Gyun, Seo, Seung‐Hwan, Shin, Ji‐Hun, Yang, Jung‐Pyo, Lee, Sang Hyung, Shin, Eun‐Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484329/
https://www.ncbi.nlm.nih.gov/pubmed/30834688
http://dx.doi.org/10.1111/jcmm.14207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484329/
https://www.ncbi.nlm.nih.gov/pubmed/30834688
http://dx.doi.org/10.1111/jcmm.14207

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