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Increase in the nuclear localization of PTEN by the Toxoplasma GRA16 protein and subsequent induction of p53‐dependent apoptosis and anticancer effect
This study investigated the efficacy of Toxoplasma GRA16, which binds to herpes virus‐associated ubiquitin‐specific protease (HAUSP), in anticancer treatment, and whether the expression of GRA16 in genetically modified hepatocellular carcinoma (HCC) cells (GRA16‐p53‐wild HepG2 and GRA16‐p53‐null Hep...
Autores principales: | Kim, Sang‐Gyun, Seo, Seung‐Hwan, Shin, Ji‐Hun, Yang, Jung‐Pyo, Lee, Sang Hyung, Shin, Eun‐Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484329/ https://www.ncbi.nlm.nih.gov/pubmed/30834688 http://dx.doi.org/10.1111/jcmm.14207 |
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