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HC diet inhibited testosterone synthesis by activating endoplasmic reticulum stress in testicular Leydig cells

Emerging epidemiological studies indicate that hypercholesterolaemia is a risk factor for testosterone deficiency. However, the underlying mechanism is unclear. Testicular Leydig cells are the primary source of testosterone in males. To identify the effect and mechanism of cholesterol overload on Le...

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Detalles Bibliográficos
Autores principales: Yu, Chunxiao, Jiang, Fangjie, Zhang, Meijie, Luo, Dandan, Shao, Shanshan, Zhao, Jiajun, Gao, Ling, Zuo, Changting, Guan, Qingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484377/
https://www.ncbi.nlm.nih.gov/pubmed/30884106
http://dx.doi.org/10.1111/jcmm.14143