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The pattern‐recognition molecule mindin binds integrin Mac‐1 to promote macrophage phagocytosis via Syk activation and NF‐κB p65 translocation

Mindin has a broad spectrum of roles in the innate immune system, including in macrophage migration, antigen phagocytosis and cytokine production. Mindin functions as a pattern‐recognition molecule for microbial pathogens. However, the underlying mechanisms of mindin‐mediated phagocytosis and its ex...

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Detalles Bibliográficos
Autores principales: Liu, Yuan‐sheng, Wang, Li‐fen, Cheng, Xiao‐Shen, Huo, Ya‐Ni, Ouyang, Xiao‐Mei, Liang, Lai‐Ying, Lin, Ying, Wu, Jian‐Feng, Ren, Jian‐Lin, Guleng, Bayasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484411/
https://www.ncbi.nlm.nih.gov/pubmed/30869196
http://dx.doi.org/10.1111/jcmm.14236