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The pattern‐recognition molecule mindin binds integrin Mac‐1 to promote macrophage phagocytosis via Syk activation and NF‐κB p65 translocation
Mindin has a broad spectrum of roles in the innate immune system, including in macrophage migration, antigen phagocytosis and cytokine production. Mindin functions as a pattern‐recognition molecule for microbial pathogens. However, the underlying mechanisms of mindin‐mediated phagocytosis and its ex...
Autores principales: | Liu, Yuan‐sheng, Wang, Li‐fen, Cheng, Xiao‐Shen, Huo, Ya‐Ni, Ouyang, Xiao‐Mei, Liang, Lai‐Ying, Lin, Ying, Wu, Jian‐Feng, Ren, Jian‐Lin, Guleng, Bayasi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484411/ https://www.ncbi.nlm.nih.gov/pubmed/30869196 http://dx.doi.org/10.1111/jcmm.14236 |
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