Mutant Lef1 controls Gata6 in sebaceous gland development and cancer

Mutations in Lef1 occur in human and mouse sebaceous gland (SG) tumors, but their contribution to carcinogenesis remains unclear. Since Gata6 controls lineage identity in SG, we investigated the link between these two transcription factors. Here, we show that Gata6 is a β‐catenin‐independent transcr...

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Detalles Bibliográficos
Autores principales: Oulès, Bénédicte, Rognoni, Emanuel, Hoste, Esther, Goss, Georgina, Fiehler, Ryan, Natsuga, Ken, Quist, Sven, Mentink, Remco, Donati, Giacomo, Watt, Fiona M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484415/
https://www.ncbi.nlm.nih.gov/pubmed/30886049
http://dx.doi.org/10.15252/embj.2018100526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484415/
https://www.ncbi.nlm.nih.gov/pubmed/30886049
http://dx.doi.org/10.15252/embj.2018100526

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