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Mutant Lef1 controls Gata6 in sebaceous gland development and cancer
Mutations in Lef1 occur in human and mouse sebaceous gland (SG) tumors, but their contribution to carcinogenesis remains unclear. Since Gata6 controls lineage identity in SG, we investigated the link between these two transcription factors. Here, we show that Gata6 is a β‐catenin‐independent transcr...
Autores principales: | Oulès, Bénédicte, Rognoni, Emanuel, Hoste, Esther, Goss, Georgina, Fiehler, Ryan, Natsuga, Ken, Quist, Sven, Mentink, Remco, Donati, Giacomo, Watt, Fiona M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484415/ https://www.ncbi.nlm.nih.gov/pubmed/30886049 http://dx.doi.org/10.15252/embj.2018100526 |
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