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Tetraspanin 1 as a mediator of fibrosis inhibits EMT process and Smad2/3 and beta‐catenin pathway in human pulmonary fibrosis

Tetraspanin 1(TSPAN1) as a clinically relevant gene target in cancer has been studied, but there is no direct in vivo or vitro evidence for pulmonary fibrosis (PF). Using reanalysing Gene Expression Omnibus data, here, we show for the first time that TSPAN1 was markedly down‐regulated in lung tissue...

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Detalles Bibliográficos
Autores principales: Liu, Gang, Wang, Yahong, Yang, Lawei, Zou, Baoan, Gao, Shenglan, Song, Zeqing, Lin, Ziying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484435/
https://www.ncbi.nlm.nih.gov/pubmed/30869194
http://dx.doi.org/10.1111/jcmm.14258