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From investigational product to active reference: evolution of oral sumatriptan efficacy versus placebo for the treatment of acute migraine episodes and potential impact in comparative analyses

Background: The relative efficacy and safety can vary among drugs over time. Sumatriptan, a first choice drug for acute migraine, can illustrate this phenomenon. Objective: To assess the evolution of the relative efficacy and tolerability of oral sumatriptan against placebo between its approval in 1...

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Detalles Bibliográficos
Autores principales: Thokagevistk, Katia, François, Clément, Brignone, Mélanie, Toumi, Mondher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Routledge 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484471/
https://www.ncbi.nlm.nih.gov/pubmed/31044055
http://dx.doi.org/10.1080/20016689.2019.1603538