Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis

Murine inflammatory caspase-11 has an important role in intestinal epithelial inflammation and barrier function. Activation of the non-canonical inflammasome, mediated by caspase-11, serves as a regulatory pathway for the production of the pro-inflammatory cytokines IL-1β and IL-18, and has a key ro...

Descripción completa

Detalles Bibliográficos
Autores principales: Flood, Brian, Manils, Joan, Nulty, Ciara, Flis, Ewelina, Kenealy, Sinead, Barber, Gillian, Fay, Joanna, Mills, Kingston H. G., Kay, Elaine W., Creagh, Emma M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484510/
https://www.ncbi.nlm.nih.gov/pubmed/30538296
http://dx.doi.org/10.1038/s41388-018-0613-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484510/
https://www.ncbi.nlm.nih.gov/pubmed/30538296
http://dx.doi.org/10.1038/s41388-018-0613-5

Ejemplares similares