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Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis

Murine inflammatory caspase-11 has an important role in intestinal epithelial inflammation and barrier function. Activation of the non-canonical inflammasome, mediated by caspase-11, serves as a regulatory pathway for the production of the pro-inflammatory cytokines IL-1β and IL-18, and has a key ro...

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Detalles Bibliográficos
Autores principales:	Flood, Brian, Manils, Joan, Nulty, Ciara, Flis, Ewelina, Kenealy, Sinead, Barber, Gillian, Fay, Joanna, Mills, Kingston H. G., Kay, Elaine W., Creagh, Emma M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484510/ https://www.ncbi.nlm.nih.gov/pubmed/30538296 http://dx.doi.org/10.1038/s41388-018-0613-5

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