Mutant Kras-induced upregulation of CD24 enhances prostate cancer stemness and bone metastasis

Prostate cancer (PCA), one of the most common malignant tumors in men, is the second leading cause of cancer deaths in males worldwide. We report here that PCA models harboring conditional LSL/Kras(G12D) or BRAF(F-V600E) allele with prostate-specific abrogated p53 function recapitulate human PCA pre...

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Detalles Bibliográficos
Autores principales: Weng, Ching-Chieh, Ding, Pei-Ya, Liu, Yu-Hsuan, Hawse, John R., Subramaniam, Malayannan, Wu, Chia-Chen, Lin, Yu-Chun, Chen, Chiao-Yun, Hung, Wen-Chun, Cheng, Kuang-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484710/
https://www.ncbi.nlm.nih.gov/pubmed/30467381
http://dx.doi.org/10.1038/s41388-018-0575-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484710/
https://www.ncbi.nlm.nih.gov/pubmed/30467381
http://dx.doi.org/10.1038/s41388-018-0575-7

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