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Fstl1/DIP2A/MGMT signaling pathway plays important roles in temozolomide resistance in glioblastoma

Temozolomide was recognized as the first-line therapy for glioblastoma to prolong the survival of patients noticeably, while recent clinical studies found that some patients were not sensitive to temozolomide treatment. The possible mechanisms seemed to be methylguanine-DNA-methyltransferase (MGMT),...

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Detalles Bibliográficos
Autores principales: Nie, Er, Miao, Faan, Jin, Xin, Wu, Weining, Zhou, Xu, Zeng, Ailiang, Yu, Tianfu, Zhi, Tongle, Shi, Zhumei, Wang, Yingyi, Zhang, Junxia, Liu, Ning, You, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484760/
https://www.ncbi.nlm.nih.gov/pubmed/30542120
http://dx.doi.org/10.1038/s41388-018-0596-2