Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma

Abnormal increases in nucleolar size and number caused by dysregulation of ribosome biogenesis has emerged as a hallmark in the majority of spontaneous cancers. The observed ribosome hyperactivity can be directly induced by the MYC transcription factors controlling the expression of RNA and protein...

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Detalles Bibliográficos
Autores principales: Hald, Øyvind H., Olsen, Lotte, Gallo-Oller, Gabriel, Elfman, Lotta Helena Maria, Løkke, Cecilie, Kogner, Per, Sveinbjörnsson, Baldur, Flægstad, Trond, Johnsen, John Inge, Einvik, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484764/
https://www.ncbi.nlm.nih.gov/pubmed/30542116
http://dx.doi.org/10.1038/s41388-018-0611-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484764/
https://www.ncbi.nlm.nih.gov/pubmed/30542116
http://dx.doi.org/10.1038/s41388-018-0611-7

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