Quantitative Characterization of α-Synuclein Aggregation in Living Cells through Automated Microfluidics Feedback Control

Aggregation of α-synuclein and formation of inclusions are hallmarks of Parkinson’s disease (PD). Aggregate formation is affected by cellular environment, but it has been studied almost exclusively in cell-free systems. We quantitatively analyzed α-synuclein inclusion formation and clearance in a ye...

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Detalles Bibliográficos
Autores principales: Perrino, Giansimone, Wilson, Cathal, Santorelli, Marco, di Bernardo, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484782/
https://www.ncbi.nlm.nih.gov/pubmed/30995486
http://dx.doi.org/10.1016/j.celrep.2019.03.081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484782/
https://www.ncbi.nlm.nih.gov/pubmed/30995486
http://dx.doi.org/10.1016/j.celrep.2019.03.081

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