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Chromatin fiber structural motifs as regulatory hubs of genome function?

Nucleosomes cover eukaryotic genomes like beads on a string and play a central role in regulating genome function. Isolated strings of nucleosomes have the potential to compact and form higher order chromatin structures, such as the well-characterized 30-nm fiber. However, despite tremendous advance...

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Detalles Bibliográficos
Autores principales: Moraru, Manuela, Schalch, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484786/
https://www.ncbi.nlm.nih.gov/pubmed/30967476
http://dx.doi.org/10.1042/EBC20180065