Perturbations in the impact of mutational activity on Vλ genes in systemic lupus erythematosus

To assess the impact of somatic hypermutation and selective influences on the Vλ light chain repertoire in systemic lupus erythematosus (SLE), the frequency and pattern of mutations were analyzed in individual CD19(+) B cells from a patient with previously undiagnosed SLE. The mutational frequency o...

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Detalles Bibliográficos
Autores principales: Dörner, Thomas, Kaschner, Sabine, Hansen, Arne, Pruss, Axel, Lipsky, Peter E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC64848/
https://www.ncbi.nlm.nih.gov/pubmed/11714391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC64848/
https://www.ncbi.nlm.nih.gov/pubmed/11714391

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