Anthecotulide Sesquiterpene Lactone Exhibits Selective Anticancer Effects in Human Malignant Melanoma Cells by Activating Apoptotic and Autophagic Pathways, S-Phase Cell Cycle Arrest, Caspase Activation, and Inhibition of NF-κB Signalling Pathway

BACKGROUND: We examined the anticancer potential of anthecotulide against SK-MEL-24 malignant melanoma cells. The apoptotic and autophagic effects of anthecotulide were also investigated. MATERIAL/METHODS: The cell viability of SK-MEL-24 human malignant melanoma cells was evaluated by WST-1 assay. F...

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Detalles Bibliográficos
Autores principales: Li, Chenyang, Han, Xiuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484873/
https://www.ncbi.nlm.nih.gov/pubmed/30997898
http://dx.doi.org/10.12659/MSM.913771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484873/
https://www.ncbi.nlm.nih.gov/pubmed/30997898
http://dx.doi.org/10.12659/MSM.913771

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