Anti-receptor activator of nuclear factor κB ligand antibody treatment increases osteoclastogenesis-promoting IL-8 in patients with rheumatoid arthritis

The receptor activator of nuclear factor κB ligand (RANKL) is an important factor for osteoclastogenesis and contributes to the pathology of rheumatoid arthritis (RA); thus, the anti-RANKL antibody (Ab) has been expected to protect joint destruction in RA patients. IL-8 also has osteoclastogenic act...

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Detalles Bibliográficos
Autores principales: Morita, Takayoshi, Shima, Yoshihito, Fujimoto, Kosuke, Tsuboi, Hideki, Saeki, Yukihiko, Narazaki, Masashi, Ogata, Atsushi, Kumanogoh, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484893/
https://www.ncbi.nlm.nih.gov/pubmed/30753461
http://dx.doi.org/10.1093/intimm/dxz009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484893/
https://www.ncbi.nlm.nih.gov/pubmed/30753461
http://dx.doi.org/10.1093/intimm/dxz009

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