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Anti-receptor activator of nuclear factor κB ligand antibody treatment increases osteoclastogenesis-promoting IL-8 in patients with rheumatoid arthritis

The receptor activator of nuclear factor κB ligand (RANKL) is an important factor for osteoclastogenesis and contributes to the pathology of rheumatoid arthritis (RA); thus, the anti-RANKL antibody (Ab) has been expected to protect joint destruction in RA patients. IL-8 also has osteoclastogenic act...

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Detalles Bibliográficos
Autores principales:	Morita, Takayoshi, Shima, Yoshihito, Fujimoto, Kosuke, Tsuboi, Hideki, Saeki, Yukihiko, Narazaki, Masashi, Ogata, Atsushi, Kumanogoh, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484893/ https://www.ncbi.nlm.nih.gov/pubmed/30753461 http://dx.doi.org/10.1093/intimm/dxz009

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