INPP4B promotes colorectal cancer cell proliferation by activating mTORC1 signaling and cap-dependent translation

BACKGROUND AND OBJECTIVE: Inositol polyphosphate 4-phosphatase type II (INPP4B) is over-expressed in CRC tissues, and emerges as an oncogene. However, the mechanism by which INPP4B regulates CRC cell proliferation remains largely unclear. In this study, we aimed to investigate the regulatory mechani...

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Detalles Bibliográficos
Autores principales: Ruan, Xin-Hua, Liu, Xi-Mei, Yang, Zhi-Xiang, Zhang, Shao-Peng, Li, Quan-Zheng, Lin, Chun-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485035/
https://www.ncbi.nlm.nih.gov/pubmed/31114251
http://dx.doi.org/10.2147/OTT.S186365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485035/
https://www.ncbi.nlm.nih.gov/pubmed/31114251
http://dx.doi.org/10.2147/OTT.S186365

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