Silibinin efficacy in a rat model of pulmonary arterial hypertension using monocrotaline and chronic hypoxia

BACKGROUND: C-X-C chemokine receptor type 4 (CXCR4) may be involved in the development of pulmonary arterial hypertension (PAH). CXCR4 inhibitor AMD3100 was described to have a positive effect on the prevention of pulmonary arterial muscularization in PAH models. Silibinin is a traditional medicine...

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Detalles Bibliográficos
Autores principales: Zhang, Tingting, Kawaguchi, Nanako, Yoshihara, Kenji, Hayama, Emiko, Furutani, Yoshiyuki, Kawaguchi, Kayoko, Tanaka, Takeshi, Nakanishi, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485095/
https://www.ncbi.nlm.nih.gov/pubmed/31023308
http://dx.doi.org/10.1186/s12931-019-1041-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485095/
https://www.ncbi.nlm.nih.gov/pubmed/31023308
http://dx.doi.org/10.1186/s12931-019-1041-y

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