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Gradual withdrawal of remifentanil delays initial post-operative analgesic demand after thyroid surgery; double-blinded, randomized controlled trial

BACKGROUND: Mismanagement of remifentanil leads to severe side effects such as opioid-induced tolerance and hyperalgesia. Recently studies revealed an alternative withdrawal method to limit these side effects. A gradual withdrawal of remifentanil seems to be associated with less pain. The hypothesis...

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Detalles Bibliográficos
Autores principales: Saxena, Sarah, Gonsette, Kimberly, Terram, Willy, Huybrechts, Isabelle, Nahrwold, Daniel A., Cappello, Matteo, Barvais, Luc, Engelman, Edgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485117/
https://www.ncbi.nlm.nih.gov/pubmed/31027480
http://dx.doi.org/10.1186/s12871-019-0731-9