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Learning mutational graphs of individual tumour evolution from single-cell and multi-region sequencing data
BACKGROUND: A large number of algorithms is being developed to reconstruct evolutionary models of individual tumours from genome sequencing data. Most methods can analyze multiple samples collected either through bulk multi-region sequencing experiments or the sequencing of individual cancer cells....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485126/ https://www.ncbi.nlm.nih.gov/pubmed/31023236 http://dx.doi.org/10.1186/s12859-019-2795-4 |