Balancing multiple objectives in conformation sampling to control decoy diversity in template-free protein structure prediction

BACKGROUND: Computational approaches for the determination of biologically-active/native three-dimensional structures of proteins with novel sequences have to handle several challenges. The (conformation) space of possible three-dimensional spatial arrangements of the chain of amino acids that const...

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Detalles Bibliográficos
Autores principales: Zaman, Ahmed Bin, Shehu, Amarda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485169/
https://www.ncbi.nlm.nih.gov/pubmed/31023237
http://dx.doi.org/10.1186/s12859-019-2794-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485169/
https://www.ncbi.nlm.nih.gov/pubmed/31023237
http://dx.doi.org/10.1186/s12859-019-2794-5

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