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Balancing multiple objectives in conformation sampling to control decoy diversity in template-free protein structure prediction
BACKGROUND: Computational approaches for the determination of biologically-active/native three-dimensional structures of proteins with novel sequences have to handle several challenges. The (conformation) space of possible three-dimensional spatial arrangements of the chain of amino acids that const...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485169/ https://www.ncbi.nlm.nih.gov/pubmed/31023237 http://dx.doi.org/10.1186/s12859-019-2794-5 |