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H(2)Se Induces Reductive Stress in HepG2 Cells and Activates Cell Autophagy by Regulating the Redox of HMGB1 Protein under Hypoxia

Rationale: Selenium has been shown to have chemotherapeutic effects against cancer. However, the anti-cancer mechanism of selenium is not fully understood, and the role of hydrogen selenide (H(2)Se), which is a common metabolite of dietary selenium compounds, has not been elucidated due to the lack...

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Detalles Bibliográficos
Autores principales: Pan, Xiaohong, Song, Xiaoxiao, Wang, Cheng, Cheng, Tingting, Luan, Dongrui, Xu, Kehua, Tang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485193/
https://www.ncbi.nlm.nih.gov/pubmed/31037139
http://dx.doi.org/10.7150/thno.31841