A Novel Peptide Interfering with proBDNF-Sortilin Interaction Alleviates Chronic Inflammatory Pain

Rationale: Brain-derived neurotrophic factor (BDNF) is a key mediator in the development of chronic pain. Sortilin is known to interact with proBDNF and regulate its activity-dependent secretion in cortical neurons. In a rat model of inflammatory pain with intraplantar injection of complete Freund&#...

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Detalles Bibliográficos
Autores principales: Ho, Idy H.T., Liu, Xiaodong, Zou, Yidan, Liu, Taian, Hu, Wei, Chan, Hung, Tian, Yuanyuan, Zhang, Yuchen, Li, Qing, Kou, Shanglong, Chan, Chee Sam, Gin, Tony, Cheng, Christopher H.K., Wong, Sunny H., Yu, Jun, Zhang, Lin, Wu, William K.K., Chan, Matthew T.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485195/
https://www.ncbi.nlm.nih.gov/pubmed/31037129
http://dx.doi.org/10.7150/thno.29703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485195/
https://www.ncbi.nlm.nih.gov/pubmed/31037129
http://dx.doi.org/10.7150/thno.29703

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