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Berberine Protects Glomerular Podocytes via Inhibiting Drp1-Mediated Mitochondrial Fission and Dysfunction

Elevated levels of plasma free fatty acid (FFA) and disturbed mitochondrial dynamics play crucial roles in the pathogenesis of diabetic kidney disease (DKD). However, the mechanisms by which FFA leads to mitochondrial damage in glomerular podocytes of DKD and the effects of Berberine (BBR) on podocy...

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Detalles Bibliográficos
Autores principales: Qin, Xin, Zhao, Yan, Gong, Jing, Huang, Wenya, Su, Hao, Yuan, Fen, Fang, Ke, Wang, Dingkun, Li, Jingbin, Zou, Xin, Xu, Lijun, Dong, Hui, Lu, Fuer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485199/
https://www.ncbi.nlm.nih.gov/pubmed/31037132
http://dx.doi.org/10.7150/thno.30640