Tolerizing CTL by Sustained Hepatic PD-L1 Expression Provides a New Therapy Approach in Mouse Sepsis

Cytotoxic T lymphocyte (CTL) activation contributes to liver damage during sepsis, but the mechanisms involved are largely unknown. Understanding the underlying principle will permit interference with CTL activation and thus, provide a new therapeutic option. Methods: To elucidate the mechanism lead...

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Detalles Bibliográficos
Autores principales: von Knethen, Andreas, Schäfer, Anne, Kuchler, Laura, Knape, Tilo, Christen, Urs, Hintermann, Edith, Fißlthaler, Beate, Schröder, Katrin, Brandes, Ralf P., Genz, Berit, Abshagen, Kerstin, Pützer, Brigitte M., Sha, Lisa K., Weigert, Andreas, Syed, Shahzad N., Schulz, Martin, Shah, Ajay M., Ernst, Andreas, Putyrski, Mateusz, Finkelmeier, Fabian, Pesic, Marina, Greten, Florian, Hogardt, Michael, Kempf, Volkhard A. J., Gunne, Sandra, Parnham, Michael J., Brüne, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485280/
https://www.ncbi.nlm.nih.gov/pubmed/31037153
http://dx.doi.org/10.7150/thno.28057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485280/
https://www.ncbi.nlm.nih.gov/pubmed/31037153
http://dx.doi.org/10.7150/thno.28057

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