Acidic Microenvironment Up-Regulates Exosomal miR-21 and miR-10b in Early-Stage Hepatocellular Carcinoma to Promote Cancer Cell Proliferation and Metastasis

Rationale: The incidence of hepatocellular carcinoma is rising worldwide. It is predicted that nearly half of the early-stage hepatocellular carcinoma (E-HCC) patients will develop recurrence. Dysregulated pH, a hallmark of E-HCC, is correlated with poor prognosis. The acidic microenvironment has be...

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Detalles Bibliográficos
Autores principales: Tian, Xiao-Peng, Wang, Chen-Yuan, Jin, Xiao-Han, Li, Mei, Wang, Feng-Wei, Huang, Wei-Juan, Yun, Jing-Ping, Xu, Rui-Hua, Cai, Qing-Qing, Xie, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485281/
https://www.ncbi.nlm.nih.gov/pubmed/31037150
http://dx.doi.org/10.7150/thno.30958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485281/
https://www.ncbi.nlm.nih.gov/pubmed/31037150
http://dx.doi.org/10.7150/thno.30958

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