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Acidic Microenvironment Up-Regulates Exosomal miR-21 and miR-10b in Early-Stage Hepatocellular Carcinoma to Promote Cancer Cell Proliferation and Metastasis
Rationale: The incidence of hepatocellular carcinoma is rising worldwide. It is predicted that nearly half of the early-stage hepatocellular carcinoma (E-HCC) patients will develop recurrence. Dysregulated pH, a hallmark of E-HCC, is correlated with poor prognosis. The acidic microenvironment has be...
Autores principales: | Tian, Xiao-Peng, Wang, Chen-Yuan, Jin, Xiao-Han, Li, Mei, Wang, Feng-Wei, Huang, Wei-Juan, Yun, Jing-Ping, Xu, Rui-Hua, Cai, Qing-Qing, Xie, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485281/ https://www.ncbi.nlm.nih.gov/pubmed/31037150 http://dx.doi.org/10.7150/thno.30958 |
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