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HOXB13 networking with ABCG1/EZH2/Slug mediates metastasis and confers resistance to cisplatin in lung adenocarcinoma patients

Rationale: Distant metastasis and chemoresistance are the major causes of short survival after initial chemotherapy in lung adenocarcinoma patients. However, the underlying mechanisms remain elusive. Our pilot study identified high expression of the homeodomain transcription factor HOXB13 in chemore...

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Detalles Bibliográficos
Autores principales: Zhan, Jun, Wang, Peng, Li, Shuai, Song, Jiagui, He, Huiying, Wang, Yunling, Liu, Zhaofei, Wang, Fan, Bai, Hua, Fang, Weigang, Du, Quan, Ye, Min, Chang, Zhijie, Wang, Jie, Zhang, Hongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485289/
https://www.ncbi.nlm.nih.gov/pubmed/31037158
http://dx.doi.org/10.7150/thno.29463