SarcTrack: An Adaptable Software Tool for Efficient Large-Scale Analysis of Sarcomere Function in hiPSC-Cardiomyocytes

RATIONALE: Human induced pluripotent stem cell–derived cardiomyocytes (hiPSC-CMs) in combination with CRISPR/Cas9 genome editing provide unparalleled opportunities to study cardiac biology and disease. However, sarcomeres, the fundamental units of myocyte contraction, are immature and nonlinear in h...

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Detalles Bibliográficos
Autores principales: Toepfer, Christopher N., Sharma, Arun, Cicconet, Marcelo, Garfinkel, Amanda C., Mücke, Michael, Neyazi, Meraj, Willcox, Jon A.L., Agarwal, Radhika, Schmid, Manuel, Rao, Jyoti, Ewoldt, Jourdan, Pourquié, Olivier, Chopra, Anant, Chen, Christopher S., Seidman, Jonathan G., Seidman, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
New Methods in Cardiovascular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485312/
https://www.ncbi.nlm.nih.gov/pubmed/30700234
http://dx.doi.org/10.1161/CIRCRESAHA.118.314505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485312/
https://www.ncbi.nlm.nih.gov/pubmed/30700234
http://dx.doi.org/10.1161/CIRCRESAHA.118.314505

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