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Effect of αvβ3 Integrin Expression and Activity on Intraocular Pressure

PURPOSE: To determine the effects of αvβ3 integrin expression and activation on intraocular pressure (IOP). METHODS: Cre(+/−)β3(flox/flox) mice were treated with topical tamoxifen eye drops for 5 days to activate Cre and excise the β3 integrin gene from the anterior segment. IOP was measured weekly...

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Detalles Bibliográficos
Autores principales: Faralli, Jennifer A., Filla, Mark S., Peters, Donna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485315/
https://www.ncbi.nlm.nih.gov/pubmed/31022732
http://dx.doi.org/10.1167/iovs.18-26038