Cargando…

The impact of poly-A microsatellite heterologies in meiotic recombination

Meiotic recombination has strong, but poorly understood effects on short tandem repeat (STR) instability. Here, we screened thousands of single recombinant products with sperm typing to characterize the role of polymorphic poly-A repeats at a human recombination hotspot in terms of hotspot activity...

Descripción completa

Detalles Bibliográficos
Autores principales: Heissl, Angelika, Betancourt, Andrea J, Hermann, Philipp, Povysil, Gundula, Arbeithuber, Barbara, Futschik, Andreas, Ebner, Thomas, Tiemann-Boege, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485458/
https://www.ncbi.nlm.nih.gov/pubmed/31023833
http://dx.doi.org/10.26508/lsa.201900364