CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation

Lymphocyte functions triggered by antigen recognition and cosignals imply rapid and intense cell division, hence metabolism adaptation(1). The cytidine nucleotide triphosphate (CTP) is a precursor required for the metabolism of DNA, RNA and phospholipids(2-4). CTP originates from two sources: a salv...

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Detalles Bibliográficos
Autores principales: Martin, Emmanuel, Palmic, Noé, Sanquer, Sylvia, Lenoir, Christelle, Hauck, Fabian, Mongellaz, Cédric, Fabrega, Sylvie, Nitschké, Patrick, Esposti, Mauro Degli, Schwartzentruber, Jeremy, Taylor, Naomi, Majewski, Jacek, Jabado, Nada, Wynn, Robert, Picard, Capucine, Fischer, Alain, Arkwright, Peter, Latour, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485470/
https://www.ncbi.nlm.nih.gov/pubmed/24870241
http://dx.doi.org/10.1038/nature13386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485470/
https://www.ncbi.nlm.nih.gov/pubmed/24870241
http://dx.doi.org/10.1038/nature13386

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