Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events

Adjuvanted vaccines afford invaluable protection against disease, while the molecular and cellular changes they induce offer direct insight into human immunobiology. Here we show that within 24 hours of receiving adjuvanted swine flu vaccine, healthy individuals made expansive, complex molecular and...

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Detalles Bibliográficos
Autores principales: Sobolev, Olga, Binda, Elisa, O’Farrell, Sean, Lorenc, Anna, Pradines, Joel, Huang, Yongqing, Duffner, Jay, Schulz, Reiner, Cason, John, Zambon, Maria, Malim, Michael H., Peakman, Mark, Cope, Andrew, Capila, Ishan, Kaundinya, Ganesh V., Hayday, Adrian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485475/
https://www.ncbi.nlm.nih.gov/pubmed/26726811
http://dx.doi.org/10.1038/ni.3328