Negative feedback at kinetochores underlies a responsive spindle checkpoint signal

Kinetochores are specialised multi-protein complexes that play a crucial role in maintaining genome stability 1. They bridge attachments between chromosomes and microtubules during mitosis and they activate the spindle assembly checkpoint (SAC) to arrest division until all chromosomes are attached 2...

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Detalles Bibliográficos
Autores principales: Nijenhuis, Wilco, Vallardi, Giulia, van den Dikkenberg, Antoinette, Kops, Geert JPL, Saurin, Adrian T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485516/
https://www.ncbi.nlm.nih.gov/pubmed/25402682
http://dx.doi.org/10.1038/ncb3065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485516/
https://www.ncbi.nlm.nih.gov/pubmed/25402682
http://dx.doi.org/10.1038/ncb3065

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