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Reduced Number of Lymphocytes by X-ray Irradiation: A Problem in a Combination Therapy Trial that Elicits the Abscopal Effect in Preclinical Studies Using Electron Beam Irradiation

In preclinical studies with model animals, intravenous administration of a derivative of chemokine CCL3, named eMIP, after local electron-beam irradiation, not only enhanced tumor growth inhibition at a target site but also induced tumor killing beyond the treated site (a phenomenon known as the abs...

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Detalles Bibliográficos
Autores principales: Kanegasaki, Shiro, Yamashita, Takashi, Tsuchiya, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485521/
https://www.ncbi.nlm.nih.gov/pubmed/31058025
http://dx.doi.org/10.7759/cureus.4142