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Polycythaemia Vera among Sudanese Patients with Special Emphasis on JAK2 Mutations

BACKGROUND: In recent years, a somatic point mutation in the Janus Kinase 2 (JAK2) gene (1849 G→T, V617F) has been reported to occur in over 90% of patients with polycythemia vera (PV). Another JAK2 mutation in exon 12 had been described and shown capable of activating erythropoietin signaling pathw...

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Detalles Bibliográficos
Autores principales: Ibrahim, Ibrahim Khidir, Hassan, Rosline, Ali, Elshazli Widaa, Omer, Awad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485582/
https://www.ncbi.nlm.nih.gov/pubmed/30677867
http://dx.doi.org/10.31557/APJCP.2019.20.1.41