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Activation of aryl hydrocarbon receptor signaling by a novel agonist ameliorates autoimmune encephalomyelitis

BACKGROUND: Multiple sclerosis (MS) is a widespread neurological autoimmune disease that includes episodes of demyelination in the central nervous system (CNS). The accumulated evidence has suggested that aryl hydrocarbon receptor (Ahr), a ligand-activated transcription factor, is a promising treatm...

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Detalles Bibliográficos
Autores principales: Abdullah, Alzahrani, Maged, Mohammed, Hairul-Islam M., Ibrahim, Osama I., Alwassil, Maha, Habash, Manal, Alfuwaires, Hamza, Hanieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485712/
https://www.ncbi.nlm.nih.gov/pubmed/31026283
http://dx.doi.org/10.1371/journal.pone.0215981