Optic Nerve Lipidomics Reveal Impaired Glucosylsphingosine Lipids Pathway in Glaucoma

PURPOSE: To determine major differences in lipid profile between human control and glaucomatous optic nerve. To assess major enzymes in lipid pathway if aberration is revealed for a lipid class by profiling. METHODS: Optic nerve (ON) samples were obtained from human cadaveric donors [control (n = 11...

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Detalles Bibliográficos
Autores principales: Chauhan, Muhammad Zain, Valencia, Ann-Katrin, Piqueras, Maria Carmen, Enriquez-Algeciras, Mabel, Bhattacharya, Sanjoy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485987/
https://www.ncbi.nlm.nih.gov/pubmed/31022733
http://dx.doi.org/10.1167/iovs.18-25802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485987/
https://www.ncbi.nlm.nih.gov/pubmed/31022733
http://dx.doi.org/10.1167/iovs.18-25802

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