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Can patient-reported outcomes be used instead of clinician-reported outcomes and photographs as primary endpoints of late normal tissue effects in breast radiotherapy trials? Results from the IMPORT LOW trial

BACKGROUND: In an era of low local relapse rates after adjuvant breast radiotherapy, risks of late normal-tissue effects (NTE) need to be balanced against risk of relapse. NTE are assessed using patient-reported outcome measures (PROMs), clinician-reported outcomes (CRO) and photographs. This analys...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Indrani S., Haviland, Joanne S., Hopwood, Penelope, Coles, Charlotte E., Yarnold, John R., Bliss, Judith M., Kirby, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific Publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486395/
https://www.ncbi.nlm.nih.gov/pubmed/31005219
http://dx.doi.org/10.1016/j.radonc.2019.01.036