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TGF-β-induced alternative splicing of TAK1 promotes EMT and drug resistance

Transforming growth factor-β (TGF-β) is major inducer of epithelial to mesenchymal transition (EMT), which associates with cancer cell metastasis and resistance to chemotherapy and targeted drugs, through both transcriptional and non-transcriptional mechanisms. We previously reported that in cancer...

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Detalles Bibliográficos
Autores principales: Tripathi, Veenu, Shin, Jee-Hye, Stuelten, Christina H., Zhang, Ying E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486402/
https://www.ncbi.nlm.nih.gov/pubmed/30626936
http://dx.doi.org/10.1038/s41388-018-0655-8