Topoisomerase IIβ-binding protein 1 activates expression of E2F1 and p73 in HPV positive cells for genome amplification upon epithelial differentiation

High-risk human papillomaviruses (HPVs) constitutively activate the ataxia telangiectasia mutated (ATM) and the ataxia telangiectasia and Rad3-related (ATR) DNA damage repair pathways for viral genome amplification. HPVs activate these pathways through the immune regulator STAT-5. For the ATR pathwa...

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Detalles Bibliográficos
Autores principales: Hong, Shiyuan, Xu, Junfen, Li, Yan, Andrade, Jorge, Hoover, Paul, Kaminski, Paul J., Laimins, Laimonis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486426/
https://www.ncbi.nlm.nih.gov/pubmed/30631149
http://dx.doi.org/10.1038/s41388-018-0633-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486426/
https://www.ncbi.nlm.nih.gov/pubmed/30631149
http://dx.doi.org/10.1038/s41388-018-0633-1

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