Modeling Glycan Processing Reveals Golgi-Enzyme Homeostasis upon Trafficking Defects and Cellular Differentiation

The decoration of proteins by carbohydrates is essential for eukaryotic life yet heterogeneous due to a lack of biosynthetic templates. This complex carbohydrate mixture—the glycan profile—is generated in the compartmentalized Golgi, in which level and localization of glycosylation enzymes are key d...

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Detalles Bibliográficos
Autores principales: Fisher, Peter, Spencer, Hannah, Thomas-Oates, Jane, Wood, A. Jamie, Ungar, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486481/
https://www.ncbi.nlm.nih.gov/pubmed/31018136
http://dx.doi.org/10.1016/j.celrep.2019.03.107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486481/
https://www.ncbi.nlm.nih.gov/pubmed/31018136
http://dx.doi.org/10.1016/j.celrep.2019.03.107

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