Enteropathogenic Escherichia coli Stimulates Effector-Driven Rapid Caspase-4 Activation in Human Macrophages

Microbial infections can stimulate the assembly of inflammasomes, which activate caspase-1. The gastrointestinal pathogen enteropathogenic Escherichia coli (EPEC) causes localized actin polymerization in host cells. Actin polymerization requires the binding of the bacterial adhesin intimin to Tir, w...

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Detalles Bibliográficos
Autores principales: Goddard, Philippa J., Sanchez-Garrido, Julia, Slater, Sabrina L., Kalyan, Mohini, Ruano-Gallego, David, Marchès, Olivier, Fernández, Luis Ángel, Frankel, Gad, Shenoy, Avinash R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486487/
https://www.ncbi.nlm.nih.gov/pubmed/31018119
http://dx.doi.org/10.1016/j.celrep.2019.03.100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486487/
https://www.ncbi.nlm.nih.gov/pubmed/31018119
http://dx.doi.org/10.1016/j.celrep.2019.03.100

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