Delivering SaCas9 mRNA by lentivirus-like bionanoparticles for transient expression and efficient genome editing

The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) system discovered using bacteria has been repurposed for genome editing in human cells. Transient expression of the editor proteins (e.g. Cas9 protein) is desirable to reduce the risk of mutagenesis from o...

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Detalles Bibliográficos
Autores principales: Lu, Baisong, Javidi-Parsijani, Parisa, Makani, Vishruti, Mehraein-Ghomi, Farideh, Sarhan, Walaa Mohamed, Sun, Dongjun, Yoo, Kyung Whan, Atala, Zachary P, Lyu, Pin, Atala, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486560/
https://www.ncbi.nlm.nih.gov/pubmed/30759231
http://dx.doi.org/10.1093/nar/gkz093

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