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A fat-tissue sensor couples growth to oxygen availability by remotely controlling insulin secretion

Organisms adapt their metabolism and growth to the availability of nutrients and oxygen, which are essential for development, yet the mechanisms by which this adaptation occurs are not fully understood. Here we describe an RNAi-based body-size screen in Drosophila to identify such mechanisms. Among...

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Detalles Bibliográficos
Autores principales: Texada, Michael J., Jørgensen, Anne F., Christensen, Christian F., Koyama, Takashi, Malita, Alina, Smith, Daniel K., Marple, Dylan F. M., Danielsen, E. Thomas, Petersen, Sine K., Hansen, Jakob L., Halberg, Kenneth A., Rewitz, Kim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486587/
https://www.ncbi.nlm.nih.gov/pubmed/31028268
http://dx.doi.org/10.1038/s41467-019-09943-y